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17 alpha-hydroxyprogesterone caproate

From SNPedia

news The effectiveness of 17 alpha-hydroxyprogesterone caproate for prevention of recurrent preterm birth is influenced by SNPs.

Black women

  • rs471767 homozygous for the major allele treatment significantly reduced the rate of preterm birth.
  • rs578029 who had a least one copy of the major allele, treatment significantly reduced in preterm birth


non-black women

  • a least one copy of the minor allele of rs503362 had a significant reduction with treatment
  • with at least one copy of the minor allele of rs666553 had a significant reduction in very preterm birth