AGT
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| EntrezGene | 183 |
| PheGenI | 183 |
| VariationViewer | 183 |
| ClinVar | AGT |
| GeneCards | AGT |
| dbSNP | 183 |
| Diseases | AGT |
| SADR | 183 |
| HugeNav | 183 |
| wikipedia | AGT |
| AGT | |
| gopubmed | AGT |
| EVS | AGT |
| HEFalMp | AGT |
| MyGene2 | AGT |
| 23andMe | AGT |
| UniProt | P01019 |
| Ensembl | ENSG00000135744 |
| OMIM | 106150 |
| # SNPs | 25 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs11122576 | 0 | 230,710,933 | |
| rs11568020 | 0 | 230,714,272 | |
| rs11568054 | 0 | 230,709,809 | |
| rs121912702 | 3 | 230,710,247 | |
| rs141900991 | 0 | 230,710,043 | |
| rs1926723 | 0 | 230,704,350 | |
| rs199476082 | 0 | 230,710,823 | |
| rs2004776 | 0 | 230,712,956 | |
| rs2478545 | 0 | 230,708,375 | |
| rs2493134 | 0 | 230,713,613 | |
| rs2493137 | 0 | 230,716,370 | |
| rs3789678 | 0 | 230,713,736 | |
| rs3789679 | 0 | 230,713,948 | |
| rs387906578 | 3 | 230,703,309 | |
| rs3889728 | 0 | 230,713,085 | |
| rs4762 | 0 | 230,710,231 | |
| rs5049 | 0 | 230,714,337 | |
| rs5050 | 0 | 230,714,140 | |
| rs5051 | 0 | 230,714,126 | |
| rs6687360 | 0 | 230,709,246 | |
| rs699 | 2 | 230,710,048 | |
| rs7079 | 0 | 230,702,585 | |
| rs74315283 | 3 | 230,705,933 | |
| rs747815674 | 0 | 230,709,994 | |
| rs778806374 | 0 | 230,705,970 |
The AGT gene encodes angiotensin (also known as angiotensinogen), and SNPs in AGT have been implicated in risk for hypertension and related disorders, such as heart disease and pre-eclampsia. Many polymorphisms in the AGT gene are known, though only a few are known to have medical consequences.
Studied SNPs of the AGT gene include:
- rs699, also known as M235T
- rs5051, known as A-6G, often in tight linkage with rs699
- rs4762, known as T174M
- rs3889728, known as G1035A
The AGXT gene is also sometimes called AGT so be sure not to confuse them.
