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Genoset

From SNPedia
(Redirected from Genosets)

A genoset refers to a defined set of genotypes; we have coined the term to represent the combination of alleles at 2 or more loci, especially when they are not contiguous along a chromosome. Typically, these are then related to a medical (or ancestral) consequence that arises only when a particular combination of SNPs is inherited.

Promethease understands this criteria syntax.

More information about genosets can be found in the related SNPedia blog post. Note that genosets themselves are boolean, not quantitative; each genoset is either true (present) or false (absent) in an individual, based on the genoset's criteria, in the same way that a genotype (or allele) is either present or absent. Note that if a DNA microarray platform lacks a given SNP, genosets that require it (that SNP) will not return a result during a Promethease evaluation.

Most Significant

 ReputeMagnitudeSummaryModification date
"Modification date" is a predefined property that corresponds to the date of the last modification of a subject and is provided by Semantic MediaWiki.
Gs14910testing for orientation issues17 August 2015 21:57:17
Gs3037WeGene quality control issues.8 June 2016 05:40:37
Gs3007Data Quality issue. Your data provider is reporting heterozygosity on the Y chromosome.23 October 2016 09:50:25
Gs228Bad6sickle cell affected25 October 2012 02:21:38
Gs2676APOE1/APOE15 November 2016 18:42:06
Gs216Bad62 copies of the APOE-ε4 allele25 January 2017 16:02:20
Gs121Bad5DR3/4-DQ8 individual at high risk for type-1 diabetes21 October 2011 06:04:16
Gs2615Did you mix multiple people together?13 March 2017 17:50:25
Gs2665Data Quality Warning21 September 2016 10:51:44
Gs305Bad5Likely carrier of one PiS and one PiZ Alpha-1 Antitrypsin (SERPINA1) alleles; A1AT deficiency29 April 2017 17:17:29
... further results


Most Recently Active

 ReputeMagnitudeSummaryModification date
"Modification date" is a predefined property that corresponds to the date of the last modification of a subject and is provided by Semantic MediaWiki.
Gs305Bad5Likely carrier of one PiS and one PiZ Alpha-1 Antitrypsin (SERPINA1) alleles; A1AT deficiency29 April 2017 17:17:29
Gs2321.7possible low pain sensitivity; LPS/LPS15 April 2017 02:33:34
Gs2331.7normal pain sensitivity; APS/APS, LPS/APS, and APS/HPS diplotypes15 April 2017 02:33:03
Gs234Bad1.7possible high pain sensitivity; HPS/HPS or HPS/APS15 April 2017 02:29:50
Gs278Good1.5Better episodic memory in older age31 March 2017 11:33:13
Gs2615Did you mix multiple people together?13 March 2017 17:50:25
Gs304BadFamilial hypercholesterolemia is a genetic disorder characterized by very high levels of low-density lipoprotein in the blood. Individuals with FH are less responsive to cholesterol control methods which are usually effective for people without FH (such as dietary modification and statin).1 March 2017 15:56:09
Gs216Bad62 copies of the APOE-ε4 allele25 January 2017 16:02:20
Gs1933.1effects due to MTHFR polymorphisms affecting homocysteine?5 January 2017 17:22:56
Gs2676APOE1/APOE15 November 2016 18:42:06
... further results


You can create a new genoset by clicking that link and filling in the form. But you'll still need to populate the criteria syntax.