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MC4R

From SNPedia

is agene
is mentioned by
Full namemelanocortin 4 receptor
EntrezGene4160
PheGenI4160
VariationViewer4160
ClinVarMC4R
GeneCardsMC4R
dbSNP4160
DiseasesMC4R
SADR4160
HugeNav4160
wikipediaMC4R
googleMC4R
gopubmedMC4R
EVSMC4R
HEFalMpMC4R
MyGene2MC4R
23andMeMC4R
UniProtP32245
EnsemblENSG00000166603
OMIM155541
# SNPs24
 Max MagnitudeChromosome positionSummary
rs1187299260,373,354
rs121913557060,372,202
rs121913558060,372,178
rs121913559060,372,045
rs121913560060,371,842
rs121913561060,371,529
rs121913562060,371,538
rs121913563060,371,827
rs121913564060,371,403
rs121913565060,372,061
rs121913566060,372,165
rs121913567060,371,694
rs121917829060,371,489
rs13447324060,372,245
rs13447325060,372,240
rs13447331060,371,970
rs193922685060,371,812
rs193922687060,371,513
rs22296162.160,372,043
rs52804924060,371,454
rs747681609060,371,856
rs751160202060,372,144
rs79783591060,371,544
rs808752260,373,245

Melanocortin 4 receptor is a protein that in humans is encoded by the MC4R gene. It encodes the MC4 protein, a G protein-coupled receptor that binds α-melanocyte stimulating hormone (α-MSH). In murine models MC4 receptors have been found to be involved in feeding behaviour, the regulation of metabolism, sexual behaviour, and male erectile function.Wikipedia

[PMID 27701398] Divergent effects of central melanocortin signalling on fat and sucrose preference in humans

Fat preference G252S 2
Fat preference Y80X 1
Fat preference R236C 1
Fat preference I125K 4
Fat preference C271Y 3 rs121913562
Fat preference Y35X; D37V 2 rs13447324; rs13447325
Fat preference I137T 1
Sucrose preference I125K 2
Sucrose preference E61K 2
Sucrose preference C271Y 2 rs121913562
Sucrose preference A144S 1
Sucrose preference Y35X; D37V 2 rs13447324; rs13447325
Sucrose preference F280AfsX12 1 rs193922687