rs10033900

Orientation

plus

Stabilized

plus

Make rs10033900(C;C)

Make rs10033900(C;T)

Make rs10033900(T;T)

Reference

GRCh38 38.1/141

Chromosome

4

Position

109737911

Gene

CFI

is a	snp
is	mentioned by
dbSNP	rs10033900
dbSNP (classic)	rs10033900
ClinGen	rs10033900
ebi	rs10033900
HLI	rs10033900
Exac	rs10033900
Gnomad	rs10033900
Varsome	rs10033900
LitVar	rs10033900
Map	rs10033900
PheGenI	rs10033900
Biobank	rs10033900
1000 genomes	rs10033900
hgdp	rs10033900
ensembl	rs10033900
geneview	rs10033900
scholar	rs10033900
google	rs10033900
pharmgkb	rs10033900
gwascentral	rs10033900
openSNP	rs10033900
23andMe	rs10033900
SNPshot	rs10033900
SNPdbe	rs10033900
MSV3d	rs10033900
GWAS Ctlg	rs10033900

GMAF

0.4972

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

OMIM	603075
Desc	MACULAR DEGENERATION, AGE-RELATED, 1; ARMD1
Variant
Related	also

GWAS snp
PMID	[PMID 20385826]
Trait	Age-related macular degeneration
Title	Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)
Risk Allele
P-val	9E-9
Odds Ratio	None None

[PMID 21139980] Associations of smoking, body mass index, dietary lutein, and the LIPC gene variant rs10468017 with advanced age-related macular degeneration

GWAS snp
PMID	[PMID 21665990]
Trait
Title	Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.
Risk Allele	T
P-val	4E-10
Odds Ratio	1.1800 [NR]

[PMID 21989362] No evidence of association between complement factor I genetic variant rs10033900 and age-related macular degeneration

[PMID 21906714] Evaluation of new and established age-related macular degeneration susceptibility genes in the Women's Health Initiative Sight Exam (WHI-SE) Study.

[PMID 22678500] Genetic Factors for Choroidal Neovascularization Associated with High Myopia

[PMID 19661236] Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes.

[PMID 20157352] Genetic analysis of typical wet-type age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese population.

GWAS snp
PMID	[PMID 22705344]
Trait
Title	Heritability and Genome-Wide Association Study to Assess Genetic Differences between Advanced Age-Related Macular Degeneration Subtypes.
Risk Allele	T
P-val	6E-9
Odds Ratio	1.3100 None

[PMID 22815349] Genetic, behavioral, and sociodemographic risk factors for second eye progression in age-related macular degeneration.