rs10984447
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 2 | >1.17x increased risk for multiple sclerosis |
| (A;G) | 2 | 1.17x increased risk for multiple sclerosis |
| (G;G) | 1 | Normal risk for multiple sclerosis |
| Reference | GRCh38 38.1/141 |
| Chromosome | 9 |
| Position | 119222275 |
| Gene | BRINP1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10984447 |
| dbSNP (classic) | rs10984447 |
| ClinGen | rs10984447 |
| ebi | rs10984447 |
| HLI | rs10984447 |
| Exac | rs10984447 |
| Gnomad | rs10984447 |
| Varsome | rs10984447 |
| LitVar | rs10984447 |
| Map | rs10984447 |
| PheGenI | rs10984447 |
| Biobank | rs10984447 |
| 1000 genomes | rs10984447 |
| hgdp | rs10984447 |
| ensembl | rs10984447 |
| geneview | rs10984447 |
| scholar | rs10984447 |
| rs10984447 | |
| pharmgkb | rs10984447 |
| gwascentral | rs10984447 |
| openSNP | rs10984447 |
| 23andMe | rs10984447 |
| SNPshot | rs10984447 |
| SNPdbe | rs10984447 |
| MSV3d | rs10984447 |
| GWAS Ctlg | rs10984447 |
| GMAF | 0.1657 |
| Max Magnitude | 2 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs10984447 has been reported in a large study to be associated with multiple sclerosis.
The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with this allele is 1.17 (CI 1.09-1.25). [PMID 17660530]
| GWAS | |
|---|---|
| SNP | rs10984447 |
| PubMedID | [PMID 17660530] |
| Condition | Multiple sclerosis |
| Gene | DBC1 |
| Risk Allele | A |
| pValue | 8.00E-006 |
| OR | 1.17 |
| 95% CI | 1.09-1.25 |
[PMID 22492128] Association of SNPs rs6498169 and rs10984447 with multiple sclerosis in Saudi patients: a model of the usefulness of familial aggregates in identifying genetic linkage in a multifactorial disease.
