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rs11052552

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 1.4x risk of type-1 diabetes
(G;T) 1.5x risk of type-1 diabetes
(T;T) 0 normal
ReferenceGRCh38 38.1/141
Chromosome12
Position9703362
GeneLOC105369652
is asnp
is mentioned by
dbSNPrs11052552
dbSNP (classic)rs11052552
ClinGenrs11052552
ebirs11052552
HLIrs11052552
Exacrs11052552
Gnomadrs11052552
Varsomers11052552
LitVarrs11052552
Maprs11052552
PheGenIrs11052552
Biobankrs11052552
1000 genomesrs11052552
hgdprs11052552
ensemblrs11052552
geneviewrs11052552
scholarrs11052552
googlers11052552
pharmgkbrs11052552
gwascentralrs11052552
openSNPrs11052552
23andMers11052552
SNPshotrs11052552
SNPdbers11052552
MSV3drs11052552
GWAS Ctlgrs11052552
GMAF0.4596
Max Magnitude0
? (G;G) (G;T) (T;T) 28


rs11052552 has been reported in a large study to be associated with type-1 diabetes.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.49 (CI 1.28-1.73), and for homozygotes, 1.43 (CI 1.21-1.69). [PMID 17554300OA-icon.png]

GWAS
SNP rs11052552
PubMedID [PMID 17554300OA-icon.png]
Condition Type 1 diabetes
Gene NR
Risk Allele G
pValue 7.00E-007
OR 1.49
95% CI 1.28-1.73



[PMID 22496761OA-icon.png] Improving Power of Genome-Wide Association Studies with Weighted False Discovery Rate Control and Prioritized Subset Analysis