| Geno
|
Mag
|
Summary
|
| (C;C)
|
1.5
|
slightly less likely to go bald
|
| (C;T)
|
|
?
|
| (T;T)
|
2
|
increased risk of baldness
|
rs1385699, also known as Arg57Lys, is a SNP in the ectodysplasin A2 receptor EDAR2 gene. This gene is located on the X chromosome.
The rs1385699(T) allele, which is the most common in European populations, was found to be associated with androgenetic alopecia in a case-control study of 400 males. [PMID 18385763]
[PMID 15902657
] Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia.
[PMID 16255080] A haplotype map of the human genome.
[PMID 19737746] Population differentiation as an indicator of recent positive selection in humans: an empirical evaluation.
[PMID 20352079] Genomic and geographic distribution of private SNPs and pathways in human populations.
] Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia.
