rs17672135
From SNPedia
| Associated with coronary artery disease |
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | normal | |
| (C;T) | 1.4 | Reduced risk (0.7x) for heart disease |
| (T;T) | 2 | 1.3x risk of heart disease |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 240282296 |
| Gene | FMN2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs17672135 |
| dbSNP (classic) | rs17672135 |
| ClinGen | rs17672135 |
| ebi | rs17672135 |
| HLI | rs17672135 |
| Exac | rs17672135 |
| Gnomad | rs17672135 |
| Varsome | rs17672135 |
| LitVar | rs17672135 |
| Map | rs17672135 |
| PheGenI | rs17672135 |
| Biobank | rs17672135 |
| 1000 genomes | rs17672135 |
| hgdp | rs17672135 |
| ensembl | rs17672135 |
| geneview | rs17672135 |
| scholar | rs17672135 |
| rs17672135 | |
| pharmgkb | rs17672135 |
| gwascentral | rs17672135 |
| openSNP | rs17672135 |
| 23andMe | rs17672135 |
| SNPshot | rs17672135 |
| SNPdbe | rs17672135 |
| MSV3d | rs17672135 |
| GWAS Ctlg | rs17672135 |
| GMAF | 0.1084 |
| Max Magnitude | 2 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs17672135 has been reported in a large study to be associated with heart disease, in particular, coronary artery disease.
The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 0.70 (CI 0.61-0.81), and for homozygotes, 1.32 (CI 0.79-2.22). [PMID 17554300
]
| GWAS | |
|---|---|
| SNP | rs17672135 |
| PubMedID | [PMID 17554300]
|
| Condition | Coronary disease |
| Gene | NR |
| Risk Allele | C |
| pValue | 2.00E-006 |
| OR | 1.43 |
| 95% CI | 1.23-1.64 |
[PMID 19956433] Genetics of coronary artery disease: focus on genome-wide association studies.
[PMID 20017983] Evaluation of population impact of candidate polymorphisms for coronary heart disease in the Framingham Heart Study Offspring Cohort.
