rs180177085

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(-;-)	7	Fanconi anemia, complementation group N
(-;T)	3	2-4 fold higher risk for breast cancer, depending on family history
(T;T)	0	common in clinvar

Reference

GRCh38 38.1/141

Chromosome

16

Position

23636151

Gene

PALB2

is a	snp
is	mentioned by
dbSNP	rs180177085
dbSNP (classic)	rs180177085
ClinGen	rs180177085
ebi	rs180177085
HLI	rs180177085
Exac	rs180177085
Gnomad	rs180177085
Varsome	rs180177085
LitVar	rs180177085
Map	rs180177085
PheGenI	rs180177085
Biobank	rs180177085
1000 genomes	rs180177085
hgdp	rs180177085
ensembl	rs180177085
geneview	rs180177085
scholar	rs180177085
google	rs180177085
pharmgkb	rs180177085
gwascentral	rs180177085
openSNP	rs180177085
23andMe	rs180177085
SNPshot	rs180177085
SNPdbe	rs180177085
MSV3d	rs180177085
GWAS Ctlg	rs180177085

Max Magnitude

7

ClinVar
Risk	Rs180177085(-;-)
Alt	Rs180177085(-;-)
Reference	Rs180177085(T;T)
Significance	Pathogenic
Disease	Fanconi anemia
Variation	info
Gene	PALB2
CLNDBN	Fanconi anemia, complementation group N
Reversed	1
HGVS	NC_000016.9:g.23647472delA
CLNSRC	PALB2 database
CLNACC	RCV000114636.1,

[PMID 17200671] Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer.