rs180177111

minus

Geno	Mag	Summary
(C;C)	0	common in clinvar
(C;T)	5	PALB2-related cancer risk
(T;T)	7	Fanconi anemia, complementation group N

Reference

GRCh38 38.1/141

Chromosome

16

Position

23629831

Gene

PALB2

is a	snp
is	mentioned by
dbSNP	rs180177111
dbSNP (classic)	rs180177111
ClinGen	rs180177111
ebi	rs180177111
HLI	rs180177111
Exac	rs180177111
Gnomad	rs180177111
Varsome	rs180177111
LitVar	rs180177111
Map	rs180177111
PheGenI	rs180177111
Biobank	rs180177111
1000 genomes	rs180177111
hgdp	rs180177111
ensembl	rs180177111
geneview	rs180177111
scholar	rs180177111
google	rs180177111
pharmgkb	rs180177111
gwascentral	rs180177111
openSNP	rs180177111
23andMe	rs180177111
SNPshot	rs180177111
SNPdbe	rs180177111
MSV3d	rs180177111
GWAS Ctlg	rs180177111

Max Magnitude

7

ClinVar
Risk	Rs180177111(T;T)
Alt	Rs180177111(T;T)
Reference	Rs180177111(C;C)
Significance	Other
Disease	Familial cancer of breast Breast cancer Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	PALB2
CLNDBN	Familial cancer of breast Breast cancer, susceptibility to Hereditary cancer-predisposing syndrome not provided
Reversed	1
HGVS	NC_000016.9:g.23641152G>A
CLNSRC	OMIM Allelic Variant PALB2 database
CLNACC	RCV000114521.6, RCV000144702.3, RCV000164897.2, RCV000413982.1,

[PMID 18053174 ] Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women.

[PMID 19863560] The contribution of founder mutations to early-onset breast cancer in French-Canadian women.