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rs2069762

From SNPedia

Orientationminus
Stabilizedminus
Make rs2069762(G;G)
Make rs2069762(G;T)
Make rs2069762(T;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position122456825
GeneIL2
is asnp
is mentioned by
dbSNPrs2069762
dbSNP (classic)rs2069762
ClinGenrs2069762
ebirs2069762
HLIrs2069762
Exacrs2069762
Gnomadrs2069762
Varsomers2069762
LitVarrs2069762
Maprs2069762
PheGenIrs2069762
Biobankrs2069762
1000 genomesrs2069762
hgdprs2069762
ensemblrs2069762
geneviewrs2069762
scholarrs2069762
googlers2069762
pharmgkbrs2069762
gwascentralrs2069762
openSNPrs2069762
23andMers2069762
SNPshotrs2069762
SNPdbers2069762
MSV3drs2069762
GWAS Ctlgrs2069762
GMAF0.247
Max Magnitude0
? (G;G) (G;T) (T;T) 28


[PMID 19058298] Promoter polymorphisms of IL2, IL4, and risk of gastric cancer in a high-risk Chinese population


[PMID 20184734OA-icon.png] The 4q27 locus and familial prostate cancer risk


[PMID 21648020] Haplotype-based analysis of ulcerative colitis risk loci identifies both IL2 and IL21 as susceptibility genes in Han Chinese

GWAS snp
PMID [PMID 21829393OA-icon.png]
Trait
Title Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.
Risk Allele A
P-val 5E-7
Odds Ratio 1.1200 [NR]


[PMID 22377791] Association of genetic polymorphisms of interleukins with new-onset diabetes after transplantation in renal transplantation


[PMID 16333313] Family based association analysis of the IL2 and IL15 genes in allergic disorders.


[PMID 16449530OA-icon.png] Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma.


[PMID 17152005] Associations between measles vaccine immunity and single-nucleotide polymorphisms in cytokine and cytokine receptor genes.


[PMID 17327408OA-icon.png] Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.


[PMID 17355643OA-icon.png] Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population.


[PMID 18598732OA-icon.png] Vaccine immunogenetics: bedside to bench to population.


[PMID 18628433OA-icon.png] Cervical and vulvar cancer risk in relation to the joint effects of cigarette smoking and genetic variation in interleukin 2.


[PMID 18633131OA-icon.png] Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.


[PMID 19066394OA-icon.png] Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.


[PMID 19126646OA-icon.png] Genetic polymorphisms in the cytokine genes and risk of hepatocellular carcinoma in low-risk non-Asians of USA.


[PMID 19147066OA-icon.png] Genomic and proteomic analysis of allogeneic hematopoietic cell transplant outcome. Seeking greater understanding the pathogenesis of GVHD and mortality.


[PMID 19173720OA-icon.png] Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated with CTLA4 and TGFbeta gene variants.


[PMID 19356949OA-icon.png] Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.


[PMID 19450131OA-icon.png] Application of pharmacogenomics to vaccines.


[PMID 19523143] Multiple sclerosis association study with the TENR-IL2-IL21 region in a Spanish population.


[PMID 20811626OA-icon.png] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.


[PMID 21649724] Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country.


[PMID 21875636OA-icon.png] Associations between single nucleotide polymorphisms and haplotypes in cytokine and cytokine receptor genes and immunity to measles vaccination.


[PMID 23172754OA-icon.png] Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility


[PMID 23487197] Association of Interleukin 2 (IL-2), Interleukin 6 (IL-6), and TNF-alpha (TNFα) Gene Polymorphisms With Paranoid Schizophrenia in a Polish Population


[PMID 25037274] Autoimmune diseases association study with the KIAA1109-IL2-IL21 region in a Tunisian population


[PMID 26550166OA-icon.png] Lack of association between interleukin-2 (IL-2) gene rs2069762 polymorphism and cancer risk: a meta-analysis


[PMID 31519598] Genetic Variants of the IL2 Gene Related to Risk and Survival in Patients With Colorectal Cancer.


[PMID 32425678OA-icon.png] Polymorphisms of genes encoding cytokines predict the risk of high-grade bladder cancer and outcomes of BCG immunotherapy.


[PMID 32432788] Effects of gene polymorphism and serum levels of IL-2 and IL-6 on endometriosis.