| Geno
|
Mag
|
Summary
|
| (A;A)
|
0
|
common/normal
|
| (A;T)
|
|
?
|
| (T;T)
|
1.2
|
Slightly higher (1.25x) higher risk for breast cancer
|
rs3176336 shows an association with breast cancer in a British study involving ~2300 patients. The odds ratio for the (T;T) vs (A;A) homozygotes is 1.25 (CI: 1.11-1.42, p=0.0026).[PMID 18174243
]
[PMID 17459456] A common variant of the p16(INK4a) genetic region is associated with physical function in older people.
[PMID 19124506] Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
[PMID 19258477] Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.
]
