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rs4769874

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0
Make rs4769874(A;A)
Make rs4769874(A;G)
ReferenceGRCh38 38.1/141
Chromosome13
Position30752304
GeneALOX5AP
is asnp
is mentioned by
dbSNPrs4769874
dbSNP (classic)rs4769874
ClinGenrs4769874
ebirs4769874
HLIrs4769874
Exacrs4769874
Gnomadrs4769874
Varsomers4769874
LitVarrs4769874
Maprs4769874
PheGenIrs4769874
Biobankrs4769874
1000 genomesrs4769874
hgdprs4769874
ensemblrs4769874
geneviewrs4769874
scholarrs4769874
googlers4769874
pharmgkbrs4769874
gwascentralrs4769874
openSNPrs4769874
23andMers4769874
SNPshotrs4769874
SNPdbers4769874
MSV3drs4769874
GWAS Ctlgrs4769874
GMAF0.05051
Max Magnitude0
? (A;A) (A;G) (G;G) 28


rs4769874, also known as SG13S89, is an ALOX5AP gene SNP that has been defined as part of a haplotype potentially associated with risk for myocardial infarction or ischemic stroke. Details of this haplotype and several related studies are on the ALOX5AP page.


[PMID 17387518] Association of ALOX5AP with ischemic stroke: a population-based case-control study.


[PMID 19130089OA-icon.png] Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis.


[PMID 20592751OA-icon.png] Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study.


[PMID 24368493] Interaction between ALOX5AP and CYP3A5 gene variants significantly increases the risk for cerebral infarctions in Chinese


[PMID 25902778] Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk


[PMID 26885075OA-icon.png] A tagging ALOX5AP polymorphism and risk of ischemic stroke in a northeastern Chinese Han population.


[PMID 26944113] Arachidonate 5-lipoxygenase (ALOX5) gene polymorphism is associated with Alzheimer's disease and body mass index.


[PMID 32027251] [Relationship between Polymorphism in ALOX5, ALOX5AP and Susceptibility to Myeloid Leukemia].