rs5569
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in clinvar |
| Make rs5569(C;T) |
| Make rs5569(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 16 |
| Position | 55697923 |
| Gene | SLC6A2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs5569 |
| dbSNP (classic) | rs5569 |
| ClinGen | rs5569 |
| ebi | rs5569 |
| HLI | rs5569 |
| Exac | rs5569 |
| Gnomad | rs5569 |
| Varsome | rs5569 |
| LitVar | rs5569 |
| Map | rs5569 |
| PheGenI | rs5569 |
| Biobank | rs5569 |
| 1000 genomes | rs5569 |
| hgdp | rs5569 |
| ensembl | rs5569 |
| geneview | rs5569 |
| scholar | rs5569 |
| rs5569 | |
| pharmgkb | rs5569 |
| gwascentral | rs5569 |
| openSNP | rs5569 |
| 23andMe | rs5569 |
| SNPshot | rs5569 |
| SNPdbe | rs5569 |
| MSV3d | rs5569 |
| GWAS Ctlg | rs5569 |
| GMAF | 0.2691 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19727679
] Further evidence of association between amphetamine response and SLC6A2 gene variants (Associated with ADHD.)
[PMID 20863575] Lack of association between response of OROS-methylphenidate and norepinephrine transporter (SLC6A2) polymorphism in Korean ADHD
[PMID 17630229] Norepinephrine transporter polymorphisms T-182C and G1287A are not associated with alcohol dependence and its clinical subgroups.
[PMID 17917281] No association of the G1287A polymorphism in the norepinephrine transporter gene and susceptibility to major depressive disorder in a Japanese population.
[PMID 17994190] Norepinephrine transporter and catecholamine-O-methyltransferase gene variants and attention-deficit/hyperactivity disorder symptoms in adults.
[PMID 18081710] Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression.
[PMID 18180394] Genetic variation within adrenergic pathways determines in vivo effects of presynaptic stimulation in humans.
[PMID 18779921] The combined effect of norepinephrine transporter gene and negative life events in major depression of Chinese Han population.
[PMID 18937309] Sexually dimorphic effects of four genes (COMT, SLC6A2, MAOA, SLC6A4) in genetic associations of ADHD: a preliminary study.
[PMID 19693267] Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.
[PMID 20008943] Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study.
[PMID 21172166] Pharmacogenetics of antidepressant response.
[PMID 23442739] Psychomotor depressive symptoms may differentially respond to venlafaxine
[PMID 22727709] Evaluation of genetic models for response in a randomized clinical trial of duloxetine in major depressive disorder.
[PMID 23648227] Association between major depressive disorder and the norepinephrine transporter polymorphisms T-182C and G1287A: a meta-analysis.
[PMID 23733030] Pharmacogenetics in major depression: a comprehensive meta-analysis.
[PMID 26051731] Association study between 5-HT2A and NET gene polymorphisms and recurrent major depression disorder in Chinese han population
[PMID 26832728] Genotyping of single nucleotide polymorphisms related to attention-deficit hyperactivity disorder.
| ClinVar | |
|---|---|
| Risk | rs5569(G;G) rs5569(T;T) |
| Alt | rs5569(G;G) rs5569(T;T) |
| Reference | Rs5569(C;C) |
| Significance | Probable-non-pathogenic |
| Disease | Orthostatic intolerance |
| Variation | info |
| Gene | SLC6A2 |
| CLNDBN | Orthostatic intolerance |
| Reversed | 1 |
| HGVS | NC_000016.9:g.55731835G>A |
| CLNSRC | |
| CLNACC | RCV000394956.1, |
[PMID 33340618] Association between genetic variants of the norepinephrine transporter gene (SLC6A2) and bipolar I disorder.
