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rs6025(A;A)

From SNPedia

11.4x higher risk of thrombosis
Is agenotype
ofrs6025
GeneF5
Chromosome1
Position169,549,811
mentionedby
Magnitude7
ReputeBad
Geno Mag Summary
(A;A) 7 11.4x higher risk of thrombosis
(A;G) 4.1 3.5-4.4x risk of thrombosis
(G;G) 0 normal/common risk of thrombosis

Significantly increased risk of thrombosis. The homozygous minor allele variant is very rare. Magnitude & Odds ratio is from a 2013 study, based on 116 subjects among cases and 24 controls. See discussion at rs6025.

Note: Independent risk for thrombosis was also seen in variants of the PT20210A or Factor 2 SNP at i3002432 (also known as rs1799963