A study of ~15,000 Europeans found that increased circulating natriuretic peptide and thus lower blood pressure and hypertension were associated with SNPs rs17376328(A), rs5068, rs198358(C), rs632793(G)
[PMID 19219041
]23andMe blog
[PMID 19326473] Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.
[PMID 20407391] Association of common variants in NPPA and NPPB with blood pressure does not translate into kidney damage in a general population study.
[PMID 21273288] Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster.
[PMID 21276798] Association of genetic variation in the natriuretic peptide system with cardiovascular outcomes.
[PMID 22785411] Genetic variation in the natriuretic peptide system, circulating natriuretic peptide levels, and blood pressure: an ambulatory blood pressure study.
[PMID 23288489] Prospective evaluation of B-type natriuretic peptide concentrations and the risk of type 2 diabetes in women.
]23andMe blog
