rs7091565

plus

Geno	Mag	Summary
(C;C)		normal
(C;T)		1.26x risk of sarcoidosis
(T;T)		1.26x risk of sarcoidosis

Reference

GRCh38 38.1/142

Chromosome

10

Position

80153805

Gene

ANXA11

is a	snp
is	mentioned by
dbSNP	rs7091565
dbSNP (classic)	rs7091565
ClinGen	rs7091565
ebi	rs7091565
HLI	rs7091565
Exac	rs7091565
Gnomad	rs7091565
Varsome	rs7091565
LitVar	rs7091565
Map	rs7091565
PheGenI	rs7091565
Biobank	rs7091565
1000 genomes	rs7091565
hgdp	rs7091565
ensembl	rs7091565
geneview	rs7091565
scholar	rs7091565
google	rs7091565
pharmgkb	rs7091565
gwascentral	rs7091565
openSNP	rs7091565
23andMe	rs7091565
SNPshot	rs7091565
SNPdbe	rs7091565
MSV3d	rs7091565
GWAS Ctlg	rs7091565

GMAF

0.4541

Max Magnitude

0

?

(C;C) (C;T) (T;T)

28

[PMID 18690218] 499 German individuals with sarcoidosis and 490 controls; Validation in an independent sample 1,649 cases, 1,832 controls. rs2789679: P = 3.0 x 10(-13), rs7091565: P = 1.0 x 10(-5)rs1049550, T > C, R230C was found to be strongly associated with sarcoidosis.

[PMID 19165924] rs2789679 P = 3.0 x 10(-13), rs7091565: P = 1.0 x 10(-5), allele-based test). Extensive fine mapping located the association signal to a region between exon 5 and exon 14 of ANXA11. A common nonsynonymous SNP (rs1049550, T > C, R230C) was found to be strongly associated with sarcoidosis