rs7529229

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(C;C)	1.4	2.5x higher risk of multiple myeloma than AA
(T;T)	0	common/normal

Make rs7529229(C;T)

Reference

GRCh38 38.1/141

Chromosome

1

Position

154448302

Gene

IL6R

is a	snp
is	mentioned by
dbSNP	rs7529229
dbSNP (classic)	rs7529229
ClinGen	rs7529229
ebi	rs7529229
HLI	rs7529229
Exac	rs7529229
Gnomad	rs7529229
Varsome	rs7529229
LitVar	rs7529229
Map	rs7529229
PheGenI	rs7529229
Biobank	rs7529229
1000 genomes	rs7529229
hgdp	rs7529229
ensembl	rs7529229
geneview	rs7529229
scholar	rs7529229
google	rs7529229
pharmgkb	rs7529229
gwascentral	rs7529229
openSNP	rs7529229
23andMe	rs7529229
SNPshot	rs7529229
SNPdbe	rs7529229
MSV3d	rs7529229
GWAS Ctlg	rs7529229

GMAF

0.4642

Max Magnitude

1.4

?	(C;C) (C;T) (T;T)	28

[PMID 19124510] multiple myeloma

• rs1801278 [C/T versus C/C genotypes; OR, 4.3; 95% confidence interval (CI), 1.5-12.1]
• rs6684439 (T/T versus C/C; OR, 2.9; 95% CI, 1.2-7.0)
• rs7529229 (C/C versus T/T; OR, 2.5; 95% CI, 1.1-6.0)
• rs8192284 (C/C versus A/A; OR, 2.5, 95% CI, 1.1-6.0)

[PMID 22421340] The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

[PMID 23111417] Interleukin-6 receptor pathways in abdominal aortic aneurysm

[PMID 23073775] Association of two variants in the interleukin-6 receptor gene and premature coronary heart disease in a Chinese Han population.

[PMID 24971337] An Association Study between Genetic Polymorphism in the Interleukin-6 Receptor Gene and Coronary Heart Disease