rs80359309

plus

Geno	Mag	Summary
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs80359309(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32333291

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359309
dbSNP (classic)	rs80359309
ClinGen	rs80359309
ebi	rs80359309
HLI	rs80359309
Exac	rs80359309
Gnomad	rs80359309
Varsome	rs80359309
LitVar	rs80359309
Map	rs80359309
PheGenI	rs80359309
Biobank	rs80359309
1000 genomes	rs80359309
hgdp	rs80359309
ensembl	rs80359309
geneview	rs80359309
scholar	rs80359309
google	rs80359309
pharmgkb	rs80359309
gwascentral	rs80359309
openSNP	rs80359309
23andMe	rs80359309
SNPshot	rs80359309
SNPdbe	rs80359309
MSV3d	rs80359309
GWAS Ctlg	rs80359309

Status

Merged into rs80359307

Max Magnitude

6

rs80359309, also known as c.1813delA, 2041delA, c.1813_1813delA and p.Ile605Tyrfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

rs80359309 has merged into rs80359307

ClinVar
Risk
Alt
Reference	Rs80359309(A;A)
Significance	Pathogenic
Disease	Breast-ovarian cancer not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Reversed	0
HGVS	NC_000013.10:g.32907428delA
CLNSRC	Breast Cancer Information Core (BRCA2) Inc.
CLNACC	RCV000031344.9, RCV000043896.5, RCV000132177.3, RCV000203637.1,