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TNF

From SNPedia
is agene
is mentioned by
Full nametumor necrosis factor
EntrezGene7124
PheGenI7124
VariationViewer7124
ClinVarTNF
GeneCardsTNF
dbSNP7124
DiseasesTNF
SADR7124
HugeNav7124
wikipediaTNF
googleTNF
gopubmedTNF
EVSTNF
HEFalMpTNF
MyGene2TNF
23andMeTNF
UniProtP01375
EnsemblENSG00000232810
OMIM191160
# SNPs17
 Max MagnitudeChromosome positionSummary
rs1799724231,574,705
rs179996431,574,531
rs1800610031,576,050
rs18006292.531,575,254
rs1800630031,574,699
rs1800750031,575,186
rs281865419031,577,157
rs3093662031,576,412
rs3093664031,576,865
rs3093665031,577,614
rs3093668031,578,718
rs3093726431,579,012
rs361525031,575,324
rs424815831,574,756
rs464584331,576,785
rs5603601531,575,287
rs673031,575,318

The TNF gene, also known as TNF-alpha, encodes a cytokine with broad inflammatory and immune related functions.


Among the best studied TNF SNPs are two found in the promoter, both of which may influence either constitutive or induced TNF expression. These 2 SNPs are:


Other TNF SNPs include:


Several studied TNF SNPs lack an entry in dbSNP; these include SNPs at positions -1036, -488, -148, and +252.