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WT1

From SNPedia
is agene
is mentioned by
Full nameWilms tumor 1
EntrezGene7490
PheGenI7490
VariationViewer7490
ClinVarWT1
GeneCardsWT1
dbSNP7490
DiseasesWT1
SADR7490
HugeNav7490
wikipediaWT1
googleWT1
gopubmedWT1
EVSWT1
HEFalMpWT1
MyGene2WT1
23andMeWT1
UniProtP19544
EnsemblENSG00000184937
OMIM607102
# SNPs37
 Max MagnitudeChromosome positionSummary
rs1057519745032,396,363
rs10605012537.532,428,031
rs1219079007.532,392,020
rs121907901032,392,704
rs121907902032,392,013
rs121907903032,392,019
rs121907904032,396,313
rs121907905032,392,723
rs1219079067.532,392,717
rs121907907032,392,682
rs1219079087.532,400,025
rs1219079097.532,392,032
rs121907910032,392,705
rs1219079117.532,434,815
rs16754032,396,399
rs1799925032,435,016
rs1799937032,389,228
rs2234581032,435,180
rs2234582032,435,148
rs2234583032,434,752
rs2234593032,392,787
rs28941777032,392,053
rs28941778932,392,014
rs28941779932,392,026
rs28942089932,392,672
rs3930513032,433,981
rs5030141032,434,307
rs5030315032,388,970
rs5030317032,388,791
rs5030320032,388,456
rs5877765737.532,417,633
rs5877765747.532,399,967
rs587776575032,391,966
rs5877765767.532,391,967
rs587776577032,391,968
rs776155094032,435,210
rs869025561032,392,755


The WT1 gene located on chromosome 11 encodes the Wilms tumor protein.Wikipedia

Several dominantly inherited syndromes are associated with de novo germline mutations in and/or deletions of the WT1 gene, including GHR:

  • Denys-Drash syndrome
  • Frasier syndrome
  • Congenital nephrotic syndrome
  • Cytogenetically normal acute myeloid leukemia
  • Prostate cancer
  • WAGR syndrome
  • Kidney cancer (Wilms tumor)


A ClinGen Actionability summary is available here and is associated with certain WT1 genotypes.