Glanzmann's thrombasthenia
From SNPedia
At a minimum, these SNPs are known to be related, and others may also be
Glanzmann's thrombasthenia is an abnormality of the platelets. It is a rare coagulopathy (bleeding disorder due to a blood abnormality), in which the platelets contain defective or low levels of glycoprotein IIb/IIIa (GpIIb/IIIa), which is a receptor for fibrinogen. As a result, no fibrinogen bridging of platelets to other platelets can occur, and the bleeding time is significantly prolonged.Wikipedia
Although it may be acquired as an autoimmune disorder, there are also autosomal recessive, and, dominant forms of Glanzmann's thrombasthenia caused by mutations in either the ITGA2B or ITGB3 genes. The dominant form is known as platelet-type bleeding disorder-16.
