Gs294
From SNPedia
| Gs294 | |
|---|---|
| Magnitude | 2 |
| Repute | Bad |
| Summary | Iron overload may contribute to increased risk of Alzheimer's disease |
| Criteria | Gs294/criteria |
rs1799945 H63D and rs1130459 -2G/A
HFE 63HH × TF -2AA synergy factor = 2.0 (1.3–3.05; 0.002) for Northern Europeans
However, HFE 63HH might be associated with higher age of onset for AD. [PMID 20817350]
