Hereditary fructosuria

At a minimum, these SNPs are known to be related, and others may also be

	Max Magnitude
rs1057516379	0
rs1057516534	0
rs1057516902	0
rs1057517091	0
rs1057517133	0
rs1057517421	0
rs118204425	3
rs118204426	3
rs118204428	3
rs118204429	0
rs118204430	3
rs138121153	0
rs145078268	3
rs1800546	3.5
rs369586696	0
rs387906225	3
rs387906226	3
rs41281039	0
rs750026492	0
rs764826805	3
rs76917243	5
rs77718928	3
rs78340951	3
rs786204503	3
rs786204598	3
rs864309533	3

http://en.wikipedia.org/wiki/Essential_fructosuria

There are many known mutations in the ALDOB gene that cause hereditary fructosuria.

23andMe reports on the four most common mutations accounting for about 75% of the HFI-causing mutations in those of European ancestry:

• rs1800546, aka A149P, accounting for 65% of all HFI-causing mutations; 1% of all Brits carry a copy
• rs76917243 or i5008215, aka A174D; accounts for 11-14% of the HFI-causing mutations
• rs78340951 or i5012664, aka N334K; 5-8% of people with HFI
• i5012665, aka delta4E4; about 3% of the HFI-causing mutations