| 0.8x reduced risk of multiple myeloma, general reduced risk of cancer |
| Geno
|
Mag
|
Summary
|
| (A;A)
|
1.7
|
0.5x reduced risk of multiple myeloma, general reduced risk of cancer
|
| (A;G)
|
1.5
|
0.8x reduced risk of multiple myeloma, general reduced risk of cancer
|
| (G;G)
|
1
|
Increased risk of multiple myeloma, B-cell neoplasms, and cancer in general
|
A number of studies with lowish p-values but low heterogeneity across studies show a reduced risk of multiple myeloma, greater in homozygotes, for the A allele. There is also a generalized reduction in cancer risk. B-cell neoplasms may be particularly affected.
