SELE
From SNPedia
| is a | gene |
| is | mentioned by |
| EntrezGene | 6401 |
| PheGenI | 6401 |
| VariationViewer | 6401 |
| ClinVar | SELE |
| GeneCards | SELE |
| dbSNP | 6401 |
| Diseases | SELE |
| SADR | 6401 |
| HugeNav | 6401 |
| wikipedia | SELE |
| SELE | |
| gopubmed | SELE |
| EVS | SELE |
| HEFalMp | SELE |
| MyGene2 | SELE |
| 23andMe | SELE |
| # SNPs | 7 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs1805193 | 0 | 169,733,631 | |
| rs2076059 | 0 | 169,729,780 | |
| rs3917406 | 0 | 169,733,137 | |
| rs5355 | 0 | 169,726,729 | |
| rs5359 | 0 | 169,723,381 | |
| rs5361 | 2.5 | 169,731,919 | |
| rs5368 | 0 | 169,727,805 |
The rs5361 Ser128Arg variation in this gene, known as E-selectin, is linked to several thrombotic disorders. [PMID 16908800]
Homozygous carriers of the Ser128Arg allele are at a 4X higher risk for recurrent venous thromboembolism (VTE); heterozygous carriers are not at increased risk. [PMID 16908800].
