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Talk:APOE

From SNPedia

Terminology[edit]

Not to pick nits, but my impression was that the alleles are named:

ApoE-ε2, ApoE-ε3, ApoE-ε4.

Whereas the proteins produced by these genes are called:

ApoE2, ApoE3, ApoE4.

Is this not correct? We need not, of course, be hypercorrect here. Just wondering.

--User:Epsilon4 2012-11-26 12:02 (UTC) 12:02, 26 November 2012 (UTC)

Quite possible. If you can find an authoritative source to back that up, we can do some edits to ensure the wiki reflects that. --- cariaso 13:59, 26 November 2012 (UTC)


That usage is what I've seen in virtually every published article I've read.

Two of many examples:

http://www.ncbi.nlm.nih.gov/pubmed/21422459

http://www.ncbi.nlm.nih.gov/pubmed/22863665

(Sometimes researchers leave out the hyphen for the genotype though, and sometimes the gene is with all caps -- as here on SNPedia.)

Wikipedia is much less reliable than most people think, but the less political the topic, the more accurate it tends to be. ApoE is not a very politically charged topic, so I would tend to trust the usage here (see top 8 or so lines):

http://en.wikipedia.org/wiki/Apolipoprotein_E#Gene

--User:Epsilon4 2012-11-26 21:10 (UTC) 21:10, 26 November 2012 (UTC)

Agreed. ApoE4 has been distinguished from ApoE-ε4 and this text is slightly improved. You are invited to rewrite as you spot other areas that need help. --- cariaso 01:34, 27 November 2012 (UTC)