BDNF
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | brain-derived neurotrophic factor |
| EntrezGene | 627 |
| PheGenI | 627 |
| VariationViewer | 627 |
| ClinVar | BDNF |
| GeneCards | BDNF |
| dbSNP | 627 |
| Diseases | BDNF |
| SADR | 627 |
| HugeNav | 627 |
| wikipedia | BDNF |
| BDNF | |
| gopubmed | BDNF |
| EVS | BDNF |
| HEFalMp | BDNF |
| MyGene2 | BDNF |
| 23andMe | BDNF |
| UniProt | P23560 |
| Ensembl | ENSG00000176697 |
| OMIM | 113505 |
| # SNPs | 31 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs10767664 | 0 | 27,704,439 | |
| rs10835210 | 0 | 27,674,363 | |
| rs11030099 | 0 | 27,656,036 | |
| rs11030100 | 0 | 27,656,039 | |
| rs11030101 | 0 | 27,659,197 | |
| rs11030103 | 0 | 27,660,786 | |
| rs11030104 | 0 | 27,662,970 | |
| rs11030107 | 0 | 27,673,288 | |
| rs11030119 | 0 | 27,706,555 | |
| rs12273363 | 0 | 27,723,312 | |
| rs12273539 | 0 | 27,661,764 | |
| rs12291063 | 0 | 27,672,554 | |
| rs13306221 | 0 | 27,701,142 | |
| rs16917234 | 0 | 27,676,827 | |
| rs16917237 | 0 | 27,680,836 | |
| rs2030323 | 0 | 27,706,992 | |
| rs2030324 | 0 | 27,705,368 | |
| rs2049045 | 0 | 27,672,694 | |
| rs2049046 | 0 | 27,702,228 | |
| rs28722151 | 0 | 27,659,629 | |
| rs41282918 | 0 | 27,657,233 | |
| rs56164415 | 0 | 27,700,188 | |
| rs61888800 | 0 | 27,700,731 | |
| rs6265 | 2.6 | 27,658,369 | |
| rs7103411 | 0 | 27,678,578 | |
| rs7103873 | 0 | 27,678,770 | |
| rs7124442 | 0 | 27,655,494 | |
| rs7127507 | 0 | 27,693,337 | |
| rs8192466 | 4 | 27,658,560 | |
| rs962369 | 0 | 27,712,873 | |
| rs988748 | 0 | 27,703,198 |
rs6265 in this gene has been linked to Alzheimer's disease.
[PMID 18518926] rs6265 aka Val66Met may influence general cognitive ability
[PMID 19018231] A study of 1749 Caucasian Americans from 250 multiplex bipolar families found evidence of association between several BDNF SNPs and risk of bipolar disorder
news SIRT1 seems to prevent a decline in levels of BDNF. People with Huntington disease tend to have low levels of BDNF.
