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From SNPedia
Magnitude 3
Repute Bad
Summary CYP2C19 Intermediate Metabolizer
Criteria Gs151/criteria

CYP2C19 Intermediate Metabolizer.

Your body breaks down some medicines at a slightly slower than normal rate (which is represented by gs150). Individuals with gs152 genotypes have even slower metabolism.

  • anti-epileptics (such as diazepam, phenytoin, and phenobarbitone)
  • anti-depressants (such as amitriptyline and clomipramine)
  • anti-platelet drug clopidogrel (Plavix)
  • anti-ulcer proton pump inhibitors like omeprazole (trade names Losec and Prilosec), esomeprazole (trade name Nexium), and lansoprazole (Prevacid)
  • hormones (estrogen, progesterone).