HLA-DRB3
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | major histocompatibility complex, class II, DR beta 3 |
| EntrezGene | 3125 |
| PheGenI | 3125 |
| VariationViewer | 3125 |
| ClinVar | HLA-DRB3 |
| GeneCards | HLA-DRB3 |
| dbSNP | 3125 |
| Diseases | HLA-DRB3 |
| SADR | 3125 |
| HugeNav | 3125 |
| wikipedia | HLA-DRB3 |
| HLA-DRB3 | |
| gopubmed | HLA-DRB3 |
| EVS | HLA-DRB3 |
| HEFalMp | HLA-DRB3 |
| MyGene2 | HLA-DRB3 |
| 23andMe | HLA-DRB3 |
| UniProt | P79483 |
| OMIM | 612735 |
| # SNPs | 1 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs2157337 | 0 | 32,533,367 |
This gene is the major histocompatibility complex, class II, DR beta 3. It plays a central role in the immune system by presenting peptides derived from extracellular proteins.
According to OMIM 612735, HLA-DRB3 is also known as HLA-DR52.
[PMID 22654557
] The DRB3 gene has 3 major alleles: DRB3*0101 (DR52a), DRB3*0202 (DR52b), and DRB3*0301 (DR52c) (5, 6), with allele frequencies 0.073, 0.136, and 0.120, respectively.
The SNP variants within this gene are listed on the DRB3 page of UniProt. (Scroll down their page.)
