Haplogroup I (Y-DNA)

Haplogroup I
Wikipedia	soon

Haplogroup I (Y-DNA) is a Y chromosome clade. A clade represents all the branches - and thus descendants - of an taxonomic (or ancestral) tree that share a single common ancestor.Wikipedia

Y-DNA Haplogroup I represents one of the twenty major branches of the Y chromosome as defined by the Y Chromosome Consortium (YCC2008). Nearly one out of five Europeans is a member. Haplogroup I probably arose in Europe because it is almost non-existent outside of Europe.

Y-DNA Haplogroup I represents one of two major European Y chromosome haplogroups (the other major haplogroup is Y Haplogroup R). Unlike R, clade I is widespread in Europe and is virtually absent elsewhere. Subclade Haplogroup I1 (Y-DNA)) is found mostly in Northern Europe, while subclade Haplogroup I2 (Y-DNA) is the most frequent haplogroup in Eastern Europe and the Balkans.[PMID 18385274]

A study of 3,000+ British men concluded that carriers of haplogroup I had about a 50% higher age-adjusted risk of coronary artery disease than did men with other Y haplogroups (for the combined populations, with an odds ratio of 1.56, CI:1.24—1.97, p=0·0002). The association between haplogroup I and coronary artery disease was independent of traditional cardiovascular and socioeconomic risk factors.[PMID 22325189] However 23andMe disputes the link to coronary artery disease.

Haplogroup I (Y-DNA) SNPs

Haplogroup I (Y-DNA) defining mutations with rsIDs below, from ISOGG 2017 (version 12.213 10th August 2017).

• rs9341301 M258, PF3721
• rs9341296 M253
• rs9341274 M227
• rs871626 CTS11042, S66
• rs7893103 L40, S156
• rs7893064 L35, PF3862, S150
• rs7893033 S155, L39
• rs7893015 L65.1, S159.1
• rs7892900 P217, PF3854, S23
• rs7892889 L38,S154
• rs7892855 L460, PF3647, S238
• rs72617687 L147.2 - derived haplogroup I2a1b2a1

- Note 1ː the same SNP is in Haplogroup J (Y-DNA) as L147.1 derived haplogroup J1a2a1a2b. Note 2ː the same SNP is in Haplogroup I (Y-DNA) as L147.3 derived haplogroup I2a2a1b2b, Note 3 the same SNP is in Haplogroup I (Y-DNA) as L147.1 derived haplogroup I1a1b1a1e2c5a,

• rs7067532 P218, S32
• rs7067482 L37, PF6900, S153
• rs3906451 L81
• rs35960273 L80
• rs35604181 L34, PF3857, S151
• rs35547782 L68, PF3781, S329
• rs35516764 L36, S152
• rs34790845 L126, S165
• rs34626372 L22, S142
• rs34441307 L137.1, S166.1
• rs3097050 L59
• rs2319818 PF3742, U179
• rs2196155 P195.2

- Noteː the same SNP is in Haplogroup N (Y-DNA) as P195.1 derived haplogroup NO1 (K2a),

• rs2032637 M72
• rs2032629 M26, PF4056
• rs2032597 M170, PF3715
• rs201671027 M359.2, P41.2

- Noteː the same SNP is in Haplogroup D (Y-DNA) as M359.1 & P41.1 derived haplogroup D1b.

• rs199865681 P37.2, PF4004
• rs17316910 P220, S119
• rs17316729 P221, PF3858, S120
• rs17316702 FGC2444, S111, V1623, Y1868
• rs17316639 L845, S110, YSC0000278, V1333
• rs17316597 M450, S109
• rs17316192 FGC2438, S108, Y1864
• rs17315723 P222, PF3861, S118, U250
• rs17315680 M436, P214, PF3856, S33
• rs17307586 L124, S64
• rs17307315 L123
• rs17307294 M438, P215, PF3853, S31
• rs17307252 CTS5783, S63
• rs17307007 L118
• rs17306657 P216, PF3855, S30
• rs17250310 FGC2426, S107, Y1863
• rs17250114 L840
• rs17249889 L41, PF3787
• rs17249791 S65, L125
• rs17222657 L157.1
• rs17222244 P223, PF3860, S117
• rs17222167 L121, S62
• rs17221964 P219, PF3859, S24
• rs17221531 L64
• rs13447354 M307.2, P203.2
• rs113822196 P38, PF3708
• rs113686221 P40
• rs112989530 L672, S327
• rs112707890 P30
• rs112137450 PF3627.2, V218.2

- Noteː the same SNP is in Haplogroup A (Y-DNA) as PF3627.1 & V218.1 derived haplogroup A1b1a1a2a1a~.

• rs111697819 L75
• rs3912 M21
• rs36044179 Page76

This haplogroup is defined in genoset Gs196.

P19 is not a SNP but a set of multiple mutations in DYS190.