| Max Magnitude | Chromosome position | Summary |
---|
rs104894853 | 0 | 149,490,322 | |
rs104894856 | 0 | 149,500,977 | |
rs104894860 | 0 | 149,498,301 | |
rs104894861 | 3 | 149,503,326 | |
rs104894862 | 0 | 149,482,935 | |
rs104894863 | 1 | 149,482,933 | |
rs1085308006 | 0 | 149,496,419 | |
rs113993945 | 0 | 149,498,132 | |
rs113993946 | 3 | 149,482,996 | |
rs113993947 | 0 | 149,498,308 | |
rs113993948 | 0 | 149,486,983 | |
rs113993949 | 3 | 149,503,477 | |
rs113993951 | 0 | 149,483,005 | |
rs113993952 | 3 | 149,503,494 | |
rs113993953 | 0 | 149,490,436 | |
rs113993954 | 0 | 149,504,185 | |
rs113993955 | 3 | 149,504,216 | |
rs1141608 | 0 | 149,501,018 | |
rs138918423 | 0 | 149,487,059 | |
rs193302904 | 0 | 149,498,223 | |
rs193302905 | 0 | 149,498,129 | |
rs193302906 | 0 | 149,487,072 | |
rs193302907 | 0 | 149,496,405 | |
rs193302908 | 0 | 149,501,031 | |
rs193302909 | 0 | 149,504,210 | |
rs193302910 | 3 | 149,503,329 | |
rs193302911 | 3 | 149,503,371 | |
rs193302912 | 0 | 149,490,385 | |
rs193302913 | 0 | 149,490,411 | |
rs193302914 | 0 | 149,501,001 | |
rs199422227 | 3 | 149,483,072 | |
rs199422228 | 3 | 149,482,894 | |
rs199422229 | 3 | 149,483,135 | |
rs199422230 | 3 | 149,482,974 | |
rs199422231 | 3 | 149,482,997 | |
rs28937310 | 0 | 149,483,135 | |
rs28937311 | 0 | 149,503,326 | |
rs398123247 | 3 | 149,505,034 | |
rs398123248 | 0 | 149,482,891 | |
rs398123249 | 3 | 149,503,468 | |
rs398123250 | 0 | 149,498,228 | |
rs398123251 | 0 | 149,498,218 | |
rs483352904 | 0 | 149,498,305 | |
rs483352905 | 0 | 149,503,379 | |
rs530501 | 0 | 149,485,920 | |
rs61736892 | 0 | 149,498,174 | |
rs781997631 | 3 | 149,504,206 | |
rs797044502 | 0 | 149,486,957 | |
rs797044671 | 0 | 149,504,188 | |
rs797044703 | 3 | 149,503,412 | |
The IDS gene, located on the X chromosome, encodes iduronate 2-sulfatase (I2S), a sulfatase enzyme. Mutations in the IDS gene are associated with a rare sex-linked lysosomal storage disease, mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome.Wikipedia
Hunter syndrome is the only MPS syndrome to exhibit X-linked recessive inheritance; other MPS syndromes are generally inherited in an autosomal recessive manner. MPS II is a condition that affects many different parts of the body and occurs almost exclusively in males. It is a progressively debilitating disorder; however, the rate of progression varies among affected individuals.GHR