IRS1
From SNPedia
| is a | gene |
| is | mentioned by |
| EntrezGene | 3667 |
| PheGenI | 3667 |
| VariationViewer | 3667 |
| ClinVar | IRS1 |
| GeneCards | IRS1 |
| dbSNP | 3667 |
| Diseases | IRS1 |
| SADR | 3667 |
| HugeNav | 3667 |
| wikipedia | IRS1 |
| IRS1 | |
| gopubmed | IRS1 |
| EVS | IRS1 |
| HEFalMp | IRS1 |
| MyGene2 | IRS1 |
| 23andMe | IRS1 |
| # SNPs | 3 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs104893642 | 0 | 226,796,916 | |
| rs1801123 | 0 | 226,796,327 | |
| rs1801278 | 0 | 226,795,828 |
[PMID 17914103] The INSR A-603G promoter SNP, which is located within a known Sp1-binding site, was associated with the risk of colorectal cancer, with carriers of the G allele having a decreased risk (odds ratios (OR) 0.71, 95% confidence interval (CI) 0.54-0.93). Carrying the variant allele of the IRS1 Gly972Arg rs1801278 SNP further decreased the risk among the INSR-603G allele carriers (OR 0.28, 95% CI 0.11-0.70)
