Moviprep
From SNPedia
MoviPrep is a prescription medicine used by adults 18 years and older to clean the colon before a colonoscopy. MoviPrep cleans your colon by causing you to have diarrhea.[1]
On the MoviPrep label, the US FDA lists G6PD deficiency as a condition with a warning as follows [2]:
Since MoviPrep contains sodium ascorbate and ascorbic acid, MoviPrep should be used with caution in patients with glucose-6-phosphate dehydrogenase (G-6-PD) deficiency, especially G-6-PD deficiency patients with an active infection, with a history of hemolysis, or taking concomitant medications known to precipitate hemolytic reactions.
| Genotype/Genoset | Diplotype | Gene | Drug Use/Category/Class | Medical Field | Summary | Descriptive Sentence |
|---|---|---|---|---|---|---|
| gs309 | WT/WT | G6PD | Colonoscopy | Gastroenterology | Normal Response Expected | You do not appear to carry any G6PD mutations linked to an unwanted side effect (hemolytic anemia). |
| gs307 | Carrier | G6PD | Colonoscopy | Gastroenterology | Use with Caution | You carry a G6PD mutation that might lead to an unwanted side effect (hemolytic anemia) when taking MoviPrep; due to variable expression (i.e. in females), enzymatic testing for G6PD activity is advisable; use with caution. |
| gs308 | G6PD-deficient | G6PD | Colonoscopy | Gastroenterology | Use with Caution | You carry a G6PD mutation linked to an unwanted side effect (hemolytic anemia) when taking MoviPrep; use with caution. |
