PCDH11X
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | protocadherin 11 X-linked |
| EntrezGene | 27328 |
| PheGenI | 27328 |
| VariationViewer | 27328 |
| ClinVar | PCDH11X |
| GeneCards | PCDH11X |
| dbSNP | 27328 |
| Diseases | PCDH11X |
| SADR | 27328 |
| HugeNav | 27328 |
| wikipedia | PCDH11X |
| PCDH11X | |
| gopubmed | PCDH11X |
| EVS | PCDH11X |
| HEFalMp | PCDH11X |
| MyGene2 | PCDH11X |
| 23andMe | PCDH11X |
| UniProt | Q9BZA7 |
| Ensembl | ENSG00000102290 |
| OMIM | 300246 |
| # SNPs | 5 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs2524861 | 0 | 91,809,191 | |
| rs2573905 | 0 | 92,147,221 | |
| rs4568761 | 0 | 92,184,068 | |
| rs5941047 | 0 | 92,176,386 | |
| rs5984894 | 0 | 92,138,738 |
The protocadherin 11 PCDH11X gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene is located in a major X/Y block of homology and its Y chromosome homolog, despite coding region changes, is still the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system.[1]
SNPs of consequence reported for PCDH11X include:
- rs5984894, associated with increased risk for Alzheimer's disease in females
