rs1036145
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Make rs1036145(A;A) |
| Make rs1036145(A;G) |
| Make rs1036145(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 150977342 |
| Gene | KCNH2, LOC107986861 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1036145 |
| dbSNP (classic) | rs1036145 |
| ClinGen | rs1036145 |
| ebi | rs1036145 |
| HLI | rs1036145 |
| Exac | rs1036145 |
| Gnomad | rs1036145 |
| Varsome | rs1036145 |
| LitVar | rs1036145 |
| Map | rs1036145 |
| PheGenI | rs1036145 |
| Biobank | rs1036145 |
| 1000 genomes | rs1036145 |
| hgdp | rs1036145 |
| ensembl | rs1036145 |
| geneview | rs1036145 |
| scholar | rs1036145 |
| rs1036145 | |
| pharmgkb | rs1036145 |
| gwascentral | rs1036145 |
| openSNP | rs1036145 |
| 23andMe | rs1036145 |
| SNPshot | rs1036145 |
| SNPdbe | rs1036145 |
| MSV3d | rs1036145 |
| GWAS Ctlg | rs1036145 |
| GMAF | 0.2309 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
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g2b2mh (sourced from [PMID 19412172
]) rs3800779 rs748693 and rs1036145 are associated with a variety of brain parameters such as hippocampal volume, hippocampal activity (declarative memory task) and activity in the dorsolateral prefrontal cortex (DLPFC). The main suggestion of how these variants in KCNH2 might lead to these brain changes and risk for schizophrenia comes from previous findings that mutations in this gene screw up the efflux of K+ ions during the repolarization phase of an action potential.
[PMID 19490382] Genetic polymorphism of KCNH2 confers predisposition of acquired atrial fibrillation in Chinese.
