rs1042026
| Orientation | minus |
| Stabilized | minus |
| Make rs1042026(A;A) |
| Make rs1042026(A;G) |
| Make rs1042026(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 99307309 |
| Gene | ADH1B |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1042026 |
| dbSNP (classic) | rs1042026 |
| ClinGen | rs1042026 |
| ebi | rs1042026 |
| HLI | rs1042026 |
| Exac | rs1042026 |
| Gnomad | rs1042026 |
| Varsome | rs1042026 |
| LitVar | rs1042026 |
| Map | rs1042026 |
| PheGenI | rs1042026 |
| Biobank | rs1042026 |
| 1000 genomes | rs1042026 |
| hgdp | rs1042026 |
| ensembl | rs1042026 |
| geneview | rs1042026 |
| scholar | rs1042026 |
| rs1042026 | |
| pharmgkb | rs1042026 |
| gwascentral | rs1042026 |
| openSNP | rs1042026 |
| 23andMe | rs1042026 |
| SNPshot | rs1042026 |
| SNPdbe | rs1042026 |
| MSV3d | rs1042026 |
| GWAS Ctlg | rs1042026 |
| GMAF | 0.3485 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 22960999 ]
|
| Trait | Esophageal cancer (alcohol interaction) |
| Title | Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. |
| Risk Allele | |
| P-val | 3E-7 |
| Odds Ratio | 1.27 [1.16-1.38] |
[PMID 16685648] Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence.
[PMID 17185388] Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans.
[PMID 17273965] Evidence of positive selection on a class I ADH locus.
[PMID 17293864] A common coding variant in CASP8 is associated with breast cancer risk.
[PMID 18331377] Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.
[PMID 18996923] Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis.
[PMID 19094228] The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.
[PMID 19124506] Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
[PMID 19193628] ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.
[PMID 19298322] Associations and interactions between SNPs in the alcohol metabolizing genes and alcoholism phenotypes in European Americans.
[PMID 19526455] ADH1A variation predisposes to personality traits and substance dependence.
[PMID 20089146] The ADH1B Arg47His polymorphism in east Asian populations and expansion of rice domestication in history.
[PMID 24722735] Replication study of ESCC susceptibility genetic polymorphisms locating in the ADH1B-ADH1C-ADH7 cluster identified by GWAS
[PMID 30639619] Alcohol Intake Interacts with Functional Genetic Polymorphisms of Aldehyde Dehydrogenases (ALDH2) and Alcohol Dehydrogenase (ADH) to Increase Esophageal Squamous Cell Cancer Risk.
