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rs10427255

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 2.1 highest odds of photic sneeze reflex
(T;T) 0 lowest odds of photic sneeze reflex
Make rs10427255(C;T)
ReferenceGRCh38 38.1/141
Chromosome2
Position145367955
is asnp
is mentioned by
dbSNPrs10427255
dbSNP (classic)rs10427255
ClinGenrs10427255
ebirs10427255
HLIrs10427255
Exacrs10427255
Gnomadrs10427255
Varsomers10427255
LitVarrs10427255
Maprs10427255
PheGenIrs10427255
Biobankrs10427255
1000 genomesrs10427255
hgdprs10427255
ensemblrs10427255
geneviewrs10427255
scholarrs10427255
googlers10427255
pharmgkbrs10427255
gwascentralrs10427255
openSNPrs10427255
23andMers10427255
SNPshotrs10427255
SNPdbers10427255
MSV3drs10427255
GWAS Ctlgrs10427255
GMAF0.4366
Max Magnitude2.1
? (C;C) (C;T) (T;T) 28


For photic sneeze reflex, we find a novel association with rs10427255 (score 10.9 and an OR of 1.32). We also find a suggestive association with rs11856995 (score 7.13 and OR of 0.78). 10.1371/journal.pgen.1000993

The C allele appears to be associated with higher odds of photic sneezing.

GWAS snp
PMID [PMID 20585627OA-icon.png]
Trait Common traits (Other)
Title Web-based, participant-driven studies yield novel genetic associations for common traits
Risk Allele C
P-val 1E-11
Odds Ratio 1.32 [NR]