| G6PD deficiency; Hb1Ac value may need adjusting for diabetes diagnosis |
| Geno
|
Mag
|
Summary
|
| (-;G)
|
0
|
|
| (A;A)
|
4
|
G6PD deficiency; Hb1Ac value may need adjusting for diabetes diagnosis
|
| (A;G)
|
3
|
G6PD deficiency carrier; Hb1Ac value may need adjusting for diabetes diagnosis
|
| (G;-)
|
0
|
|
| (G;G)
|
0
|
common in clinvar
|
The A allele is associated with a reduction in glucose-6-phosphate dehydrogenase (G6PD) and is a diagnostic SNP of the type A- G6PD deficiency genotype. Type A- is predominantly found in individuals with African ancestry. The rs1050828 A allele is also associated with malarial resistance. Because rs1050828 is located on the X chromosome, males are either hemizygous for the normal G allele or this deficiency allele.
