rs1059703
| Orientation | minus |
| Stabilized | minus |
| Make rs1059703(C;C) |
| Make rs1059703(C;T) |
| Make rs1059703(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | X |
| Position | 154013378 |
| Gene | IRAK1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1059703 |
| dbSNP (classic) | rs1059703 |
| ClinGen | rs1059703 |
| ebi | rs1059703 |
| HLI | rs1059703 |
| Exac | rs1059703 |
| Gnomad | rs1059703 |
| Varsome | rs1059703 |
| LitVar | rs1059703 |
| Map | rs1059703 |
| PheGenI | rs1059703 |
| Biobank | rs1059703 |
| 1000 genomes | rs1059703 |
| hgdp | rs1059703 |
| ensembl | rs1059703 |
| geneview | rs1059703 |
| scholar | rs1059703 |
| rs1059703 | |
| pharmgkb | rs1059703 |
| gwascentral | rs1059703 |
| openSNP | rs1059703 |
| 23andMe | rs1059703 |
| SNPshot | rs1059703 |
| SNPdbe | rs1059703 |
| MSV3d | rs1059703 |
| GWAS Ctlg | rs1059703 |
| GMAF | 0.4305 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
The C->T (Ser532Leu, rs1059703) polymorphism of the IRAK1 gene was significantly associated with atherothrombotic cerebral infarction in a study of 3,400+ Japanese adults.[PMID 18566305]
[PMID 20500689] The Role of microRNA-146a (miR-146a) and its Target IL-1R-Associated Kinase (IRAK1) in Psoriatic Arthritis Susceptibility
[PMID 20870441] A polymorphism in the 3'-UTR of interleukin-1 receptor-associated kinase (IRAK1), a target gene of miR-146a, is associated with rheumatoid arthritis susceptibility
[PMID 17382928
] The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study.
[PMID 18987746] Association of interacting genes in the toll-like receptor signaling pathway and the antibody response to pertussis vaccination.
[PMID 19288030] Association of genetic variants with chronic kidney disease in Japanese individuals with type 2 diabetes mellitus.
[PMID 19505919] Toll-like receptor signaling pathway variants and prostate cancer mortality.
[PMID 20463618] Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.
[PMID 23233309] An activity-enhancing variant of IRAK1 and an MECP2-IRAK1 haplotype associating with increased susceptibility to rheumatoid arthritis
[PMID 23867959] Toll-like receptor genetic variants are associated with Gram-negative infections in VLBW infants
[PMID 25458699] Variants in IRAK1-MECP2 region confer susceptibility to autoimmune thyroid diseases
[PMID 32173002] IRAK1 polymorphisms are associated with susceptibility to neuromyelitis optica spectrum disorder.
