rs1062033

minus

Geno	Mag	Summary
(C;G)		increases susceptibility to postmenopausal osteoporosis
(G;G)		increases susceptibility to postmenopausal osteoporosis

Make rs1062033(C;C)

Reference

GRCh38 38.1/141

Chromosome

15

Position

51255741

Gene

CYP19A1

is a	snp
is	mentioned by
dbSNP	rs1062033
dbSNP (classic)	rs1062033
ClinGen	rs1062033
ebi	rs1062033
HLI	rs1062033
Exac	rs1062033
Gnomad	rs1062033
Varsome	rs1062033
LitVar	rs1062033
Map	rs1062033
PheGenI	rs1062033
Biobank	rs1062033
1000 genomes	rs1062033
hgdp	rs1062033
ensembl	rs1062033
geneview	rs1062033
scholar	rs1062033
google	rs1062033
pharmgkb	rs1062033
gwascentral	rs1062033
openSNP	rs1062033
23andMe	rs1062033
SNPshot	rs1062033
SNPdbe	rs1062033
MSV3d	rs1062033
GWAS Ctlg	rs1062033

GMAF

0.3365

Max Magnitude

0

?

(C;C) (C;G) (G;G)

28

Rs1062033
PubMed	[PMID 15794932]
Affy Probeset	SNP_A-1904587
Affy Orientation	reverse
On GW 5.0	1
Alleles A/B	C/G
Ancestral	G
Population
Allele	G
Case Freq.
Control Freq.
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All	-
Disease	Osteoporosis, postmenopausal (OP-M)

rs1062033 increases susceptibility to Osteoporosis, postmenopausal for carriers of the G allele [PMID 15794932]

[PMID 19419293] Association of the Aromatase Gene Alleles with Bone Mineral Density: Epidemiological and Functional Evidence

OMIM	107910
Desc	CYTOCHROME P450, FAMILY 19, SUBFAMILY A, POLYPEPTIDE 1; CYP19A1
Variant
Related	also

[PMID 20417295] Common variations in estrogen-related genes are associated with severe large-joint osteoarthritis: a multicenter genetic and functional study.

[PMID 23736221 ] The sex-specific associations of the aromatase gene with Alzheimer's disease and its interaction with IL10 in the Epistasis Project.