rs10936599
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 2 | longer telomeres, longer life? |
| (T;T) | 2 | shorter telomeres, shorter life? |
| Make rs10936599(C;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 169774313 |
| Gene | MYNN |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10936599 |
| dbSNP (classic) | rs10936599 |
| ClinGen | rs10936599 |
| ebi | rs10936599 |
| HLI | rs10936599 |
| Exac | rs10936599 |
| Gnomad | rs10936599 |
| Varsome | rs10936599 |
| LitVar | rs10936599 |
| Map | rs10936599 |
| PheGenI | rs10936599 |
| Biobank | rs10936599 |
| 1000 genomes | rs10936599 |
| hgdp | rs10936599 |
| ensembl | rs10936599 |
| geneview | rs10936599 |
| scholar | rs10936599 |
| rs10936599 | |
| pharmgkb | rs10936599 |
| gwascentral | rs10936599 |
| openSNP | rs10936599 |
| 23andMe | rs10936599 |
| SNPshot | rs10936599 |
| SNPdbe | rs10936599 |
| MSV3d | rs10936599 |
| GWAS Ctlg | rs10936599 |
| GMAF | 0.3035 |
| Max Magnitude | 2 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 20190752 ]
|
| Trait | Celiac disease |
| Title | Multiple common variants for celiac disease influencing immune gene expression |
| Risk Allele | A |
| P-val | 5E-7 |
| Odds Ratio | 1.12 [1.07-1.16] |
| GWAS snp | |
|---|---|
| PMID | [PMID 20972440]
|
| Trait | |
| Title | Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33 |
| Risk Allele | C |
| P-val | 3E-8 |
| Odds Ratio | 1.0400 [1.04-1.10] |
[PMID 21708826] TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres
| GWAS snp | |
|---|---|
| PMID | [PMID 21833088]
|
| Trait | |
| Title | Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. |
| Risk Allele | G |
| P-val | 7E-7 |
| Odds Ratio | 1.1000 [1.08-1.11] |
[PMID 22045029] Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients.
| GWAS snp | |
|---|---|
| PMID | [PMID 23535734]
|
| Trait | Telomere length |
| Title | Identification of seven loci affecting mean telomere length and their association with disease. |
| Risk Allele | T |
| P-val | 3E-31 |
| Odds Ratio | .10 [0.081-0.113] unit decrease |
[PMID 24449210] Inherited genetic susceptibility to monoclonal gammopathy of unknown significance
[PMID 24292274] A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia
[PMID 22999960] Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.
| GWAS snp | |
|---|---|
| PMID | [PMID 24163127]
|
| Trait | Bladder cancer |
| Title | Genome-wide association study identifies multiple loci associated with bladder cancer risk. |
| Risk Allele | C |
| P-val | 5E-9 |
| Odds Ratio | 1.18 [1.11-1.23] |
[PMID 24875374] Variation in the Association Between Colorectal Cancer Susceptibility Loci and Colorectal Polyps by Polyp Type
[PMID 24904205] Association between previously identified loci affecting telomere length and coronary heart disease (CHD) in Han Chinese population
[PMID 24978480] A Colorectal Cancer Susceptibility New Variant at 4q26 in the Spanish Population Identified by Genome-Wide Association Analysis
| GWAS snp | |
|---|---|
| PMID | [PMID 23955597]
|
| Trait | Multiple myeloma |
| Title | Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. |
| Risk Allele | G |
| P-val | 9E-14 |
| Odds Ratio | 1.26 [1.18-1.33] |
[PMID 28233563] Genetic predisposition to advanced biological ageing increases risk for childhood-onset recurrent major depressive disorder in a large UK sample.
[PMID 28849422] The more from East-Asian, the better: risk prediction of colorectal cancer risk by GWAS-identified SNPs among Japanese.
[PMID 29100352] Genetic variations in TERC and TERT genes are associated with renal cell carcinoma risk in a Chinese Han population.
[PMID 29299136] Genetic variations in TERC and TERT genes are associated with lung cancer risk in a Chinese Han population.
[PMID 30120764] The Association of MYNN and TERC Gene Polymorphisms and Bladder Cancer in a Turkish Population.
[PMID 30325019] Genetic determinants of telomere length and risk of pancreatic cancer: a PANDoRA study.
[PMID 32577134] Single nucleotide polymorphisms in telomere length-related genes are associated with hepatocellular carcinoma risk in the Chinese Han population.
[PMID 33163281] Prognostic value of leukocyte telomere length in renal cell carcinoma patients.
