rs11190302
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1.2 | |
| (C;T) | 1.2 | |
| (T;T) | 2 |
| Reference | GRCh38 38.1/142 |
| Chromosome | 10 |
| Position | 99873158 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs11190302 |
| dbSNP (classic) | rs11190302 |
| ClinGen | rs11190302 |
| ebi | rs11190302 |
| HLI | rs11190302 |
| Exac | rs11190302 |
| Gnomad | rs11190302 |
| Varsome | rs11190302 |
| LitVar | rs11190302 |
| Map | rs11190302 |
| PheGenI | rs11190302 |
| Biobank | rs11190302 |
| 1000 genomes | rs11190302 |
| hgdp | rs11190302 |
| ensembl | rs11190302 |
| geneview | rs11190302 |
| scholar | rs11190302 |
| rs11190302 | |
| pharmgkb | rs11190302 |
| gwascentral | rs11190302 |
| openSNP | rs11190302 |
| 23andMe | rs11190302 |
| SNPshot | rs11190302 |
| SNPdbe | rs11190302 |
| MSV3d | rs11190302 |
| GWAS Ctlg | rs11190302 |
| GMAF | 0.3393 |
| Max Magnitude | 2 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
| Rs11190302 | |
|---|---|
| PubMed | [PMID 16740596] |
| Affy Probeset | SNP_A-8415319 |
| Affy Orientation | reverse |
| On GW 5.0 | 0 |
| Alleles A/B | A/G |
| Ancestral | T |
| Population | Japanese |
| Allele | T |
| Case Freq. | 0.26 |
| Control Freq. | 0.2 |
| Odds Ratio Het | 1.39 |
| Odds Ratio Hom | 2.07 |
| Odds Ratio All | 1.44 |
| Disease | Alzheimer's disease, late-onset (LOAD) |
rs11190302 increases susceptibility to late-onset Alzheimer's disease 1.39 times for heterozygotes (CT) and 2.07 times for homozygotes (TT). [PMID 16740596]
[PMID 18452187] Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample
[PMID 18359537] DNMBP is genetically associated with Alzheimer dementia in the Belgian population.
