rs1122608
| Orientation | plus |
| Stabilized | plus |
| Make rs1122608(G;G) |
| Make rs1122608(G;T) |
| Make rs1122608(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 19 |
| Position | 11052925 |
| Gene | SMARCA4 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1122608 |
| dbSNP (classic) | rs1122608 |
| ClinGen | rs1122608 |
| ebi | rs1122608 |
| HLI | rs1122608 |
| Exac | rs1122608 |
| Gnomad | rs1122608 |
| Varsome | rs1122608 |
| LitVar | rs1122608 |
| Map | rs1122608 |
| PheGenI | rs1122608 |
| Biobank | rs1122608 |
| 1000 genomes | rs1122608 |
| hgdp | rs1122608 |
| ensembl | rs1122608 |
| geneview | rs1122608 |
| scholar | rs1122608 |
| rs1122608 | |
| pharmgkb | rs1122608 |
| gwascentral | rs1122608 |
| openSNP | rs1122608 |
| 23andMe | rs1122608 |
| SNPshot | rs1122608 |
| SNPdbe | rs1122608 |
| MSV3d | rs1122608 |
| GWAS Ctlg | rs1122608 |
| GMAF | 0.1391 |
| Max Magnitude | 0 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 24262325 ]
|
| Trait | Coronary artery disease |
| Title | Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. |
| Risk Allele | T |
| P-val | 3E-11 |
| Odds Ratio | 1.14 [1.09-1.18] |
| GWAS snp | |
|---|---|
| PMID | [PMID 21378990]
|
| Trait | Coronary heart disease |
| Title | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease |
| Risk Allele | G |
| P-val | 1E-9 |
| Odds Ratio | 1.1400 [1.09-1.18] |
| GWAS snp | |
|---|---|
| PMID | [PMID 19198609]
|
| Trait | Myocardial infarction (early onset) |
| Title | Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants |
| Risk Allele | G |
| P-val | 2E-9 |
| Odds Ratio | 1.15 [1.10-1.20] |
[PMID 24219970] Common genetic variants do not associate with CAD in familial hypercholesterolemia
[PMID 24190014] BRG1 variant rs1122608 on chromosome 19p13.2 confers protection against stroke and regulates expression of pre-mRNA-splicing factor SFRS3
[PMID 23380588] Association between PCSK9 and LDLR gene polymorphisms with coronary heart disease: case-control study and meta-analysis.
[PMID 23202125] Large-scale association analysis identifies new risk loci for coronary artery disease.
[PMID 22199011] Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies
[PMID 20835900] Genetics of diabetes complications.
[PMID 20810930] Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile
[PMID 19956433] Genetics of coronary artery disease: focus on genome-wide association studies.
[PMID 24251769] LDL-c-linked SNPs are associated with LDL-c and myocardial infarction despite lipid-lowering therapy in patients with established vascular disease
[PMID 24902015] Association of polymorphisms at LDLR locus with coronary artery disease independently from lipid profile
[PMID 29615549] Correlation of rs1122608 SNP with acute myocardial infarction susceptibility and clinical characteristics in a Chinese Han population: A case-control study.
[PMID 31507094] The genetic polymorphisms of ZC3HC1 and SMARCA4 are associated with hypertension risk.
