rs1131454
| Orientation | plus |
| Stabilized | plus |
| Make rs1131454(A;A) |
| Make rs1131454(A;G) |
| Make rs1131454(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 112911065 |
| Gene | OAS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1131454 |
| dbSNP (classic) | rs1131454 |
| ClinGen | rs1131454 |
| ebi | rs1131454 |
| HLI | rs1131454 |
| Exac | rs1131454 |
| Gnomad | rs1131454 |
| Varsome | rs1131454 |
| LitVar | rs1131454 |
| Map | rs1131454 |
| PheGenI | rs1131454 |
| Biobank | rs1131454 |
| 1000 genomes | rs1131454 |
| hgdp | rs1131454 |
| ensembl | rs1131454 |
| geneview | rs1131454 |
| scholar | rs1131454 |
| rs1131454 | |
| pharmgkb | rs1131454 |
| gwascentral | rs1131454 |
| openSNP | rs1131454 |
| 23andMe | rs1131454 |
| SNPshot | rs1131454 |
| SNPdbe | rs1131454 |
| MSV3d | rs1131454 |
| GWAS Ctlg | rs1131454 |
| Merged from | Rs3741981 |
| GMAF | 0.4867 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 21638280
] 2'-5' oligoadenylate synthetase 1 polymorphism is associated with prostate cancer
| ClinVar | |
|---|---|
| Risk | rs1131454(A;A) rs1131454(C;C) |
| Alt | rs1131454(A;A) rs1131454(C;C) |
| Reference | rs1131454(G;G) |
| Significance | Other |
| Disease | Diabetes mellitus |
| Variation | info |
| Gene | OAS1 |
| CLNDBN | Diabetes mellitus, type 1, susceptibility to |
| Reversed | 0 |
| HGVS | NC_000012.11:g.113348870G>A |
| CLNSRC | OMIM Allelic Variant UniProtKB (protein) |
| CLNACC | RCV000015022.2, |
[PMID 15732009] Variation in antiviral 2',5'-oligoadenylate synthetase (2'5'AS) enzyme activity is controlled by a single-nucleotide polymorphism at a splice-acceptor site in the OAS1 gene.
[PMID 19247438] Genetic variation in OAS1 is a risk factor for initial infection with West Nile virus in man.
[PMID 19434718] Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.
[PMID 19956101] Overview of the Rapid Response data.
[PMID 19956105] Reassessment of the type I diabetes association of the OAS1 locus.
[PMID 20079393] 2'-5'-Oligoadenylate synthetase single-nucleotide polymorphisms and haplotypes are associated with variations in immune responses to rubella vaccine.
[PMID 22710942] Evaluate the relationship between polymorphisms of OAS1 gene and susceptibility to chronic hepatitis C with high resolution melting analysis.
[PMID 23337612] Polymorphisms in the oligoadenylate synthetase gene cluster and its association with clinical outcomes of dengue virus infection.
[PMID 25205466] Mitochondrial localization of the OAS1 p46 isoform associated with a common single nucleotide polymorphism
[PMID 30131040] [Fibrogenesis Genes and Susceptibility to Coronary Atherosclerosis].
