rs1148259

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(G;G)		lowest sphingomyelin ratios
(G;T)		intermediate sphingomyelin ratios
(T;T)		highest sphingomyelin ratios

Reference

GRCh38 38.1/142

Chromosome

10

Position

37219522

Gene

ANKRD30A

is a	snp
is	mentioned by
dbSNP	rs1148259
dbSNP (classic)	rs1148259
ClinGen	rs1148259
ebi	rs1148259
HLI	rs1148259
Exac	rs1148259
Gnomad	rs1148259
Varsome	rs1148259
LitVar	rs1148259
Map	rs1148259
PheGenI	rs1148259
Biobank	rs1148259
1000 genomes	rs1148259
hgdp	rs1148259
ensembl	rs1148259
geneview	rs1148259
scholar	rs1148259
google	rs1148259
pharmgkb	rs1148259
gwascentral	rs1148259
openSNP	rs1148259
23andMe	rs1148259
SNPshot	rs1148259
SNPdbe	rs1148259
MSV3d	rs1148259
GWAS Ctlg	rs1148259

GMAF

0.4867

Max Magnitude

0

?	(G;G) (G;T) (T;T)	28

rs1148259 is a SNP located in the ankyrin repeat domain 30A ANKRD30A gene.

A study of metabolite concentrations in the blood of 284 adult males from Southern Germany determined that several SNPs were associated either directly with a metabolite range or with a ratio of metabolites. The rarer rs1148259(T) allele was associated with increased sphingomyelin ratios. 10.1371/journal.pgen.1000282

GWAS snp
PMID	[PMID 19043545]
Trait	Serum metabolites
Title	Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum
Risk Allele
P-val	3E-9
Odds Ratio	NR NR