rs1154404
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Make rs1154404(A;A) |
| Make rs1154404(A;T) |
| Make rs1154404(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 99087853 |
| Gene | ADH5, LOC100507053 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1154404 |
| dbSNP (classic) | rs1154404 |
| ClinGen | rs1154404 |
| ebi | rs1154404 |
| HLI | rs1154404 |
| Exac | rs1154404 |
| Gnomad | rs1154404 |
| Varsome | rs1154404 |
| LitVar | rs1154404 |
| Map | rs1154404 |
| PheGenI | rs1154404 |
| Biobank | rs1154404 |
| 1000 genomes | rs1154404 |
| hgdp | rs1154404 |
| ensembl | rs1154404 |
| geneview | rs1154404 |
| scholar | rs1154404 |
| rs1154404 | |
| pharmgkb | rs1154404 |
| gwascentral | rs1154404 |
| openSNP | rs1154404 |
| 23andMe | rs1154404 |
| SNPshot | rs1154404 |
| SNPdbe | rs1154404 |
| MSV3d | rs1154404 |
| GWAS Ctlg | rs1154404 |
| GMAF | 0.2612 |
| Max Magnitude | 0 |
| ? | (A;A) (A;T) (T;T) | 28 |
|---|---|---|
|
| ||
linked to asthma
[PMID 17543375
] Carrying 1 or 2 copies of the minor allele of SNP rs1154404 was associated with decreased risk of asthma (relative risk [RR], 0.77; 95% CI, 0.61-0.97; P = .028 for 1 copy and RR, 0.66; 95% CI, 0.44-0.99; P = .046 for 2 copies). Homozygosity for the minor allele increased risk of asthma (RR, 1.60; 95% CI, 1.13-2.26; P = .0077).
CLINICAL IMPLICATIONS: The association of GSNOR polymorphisms with asthma suggests a potential therapeutic target.
