rs11898505

Orientation

plus

Stabilized

plus

Make rs11898505(A;A)

Make rs11898505(A;G)

Make rs11898505(G;G)

Reference

GRCh38 38.1/141

Chromosome

2

Position

54457420

Gene

SPTBN1

is a	snp
is	mentioned by
dbSNP	rs11898505
dbSNP (classic)	rs11898505
ClinGen	rs11898505
ebi	rs11898505
HLI	rs11898505
Exac	rs11898505
Gnomad	rs11898505
Varsome	rs11898505
LitVar	rs11898505
Map	rs11898505
PheGenI	rs11898505
Biobank	rs11898505
1000 genomes	rs11898505
hgdp	rs11898505
ensembl	rs11898505
geneview	rs11898505
scholar	rs11898505
google	rs11898505
pharmgkb	rs11898505
gwascentral	rs11898505
openSNP	rs11898505
23andMe	rs11898505
SNPshot	rs11898505
SNPdbe	rs11898505
MSV3d	rs11898505
GWAS Ctlg	rs11898505

GMAF

0.1988

Max Magnitude

0

?	(A;A) (A;G) (G;G)	28

rs11898505 increases susceptibility to Osteoporotic fractures for carriers of the G allele [PMID 18445777]

GWAS snp
PMID	[PMID 19079262]
Trait	Bone mineral density (spine)
Title	New sequence variants associated with bone mineral density
Risk Allele	G
P-val	0.000004
Odds Ratio	0.07 [0.04-0.10] SD decrease

GWAS snp
PMID	[PMID 19801982]
Trait	Bone mineral density (spine)
Title	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
Risk Allele	A
P-val	2E-8
Odds Ratio	0.07 [0.05-0.09] sd increase

[PMID 19629617] Replication study of candidate genes/loci associated with osteoporosis based on genome-wide screening.

[PMID 20554715] Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.

[PMID 22798246] The influence of the genetic and non-genetic factors on bone mineral density and osteoporotic fractures in Chinese women.

GWAS snp
PMID	[PMID 24430505]
Trait	Bone properties (heel)
Title	Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium.
Risk Allele	G
P-val	4E-13
Odds Ratio	.06 [0.05-0.08] unit decrease