Have questions? Visit https://www.reddit.com/r/SNPedia

rs12243326

From SNPedia

Orientationplus
Stabilizedplus
Make rs12243326(C;C)
Make rs12243326(C;T)
Make rs12243326(T;T)
ReferenceGRCh38 38.1/142
Chromosome10
Position113029056
GeneTCF7L2
is asnp
is mentioned by
dbSNPrs12243326
dbSNP (classic)rs12243326
ClinGenrs12243326
ebirs12243326
HLIrs12243326
Exacrs12243326
Gnomadrs12243326
Varsomers12243326
LitVarrs12243326
Maprs12243326
PheGenIrs12243326
Biobankrs12243326
1000 genomesrs12243326
hgdprs12243326
ensemblrs12243326
geneviewrs12243326
scholarrs12243326
googlers12243326
pharmgkbrs12243326
gwascentralrs12243326
openSNPrs12243326
23andMers12243326
SNPshotrs12243326
SNPdbers12243326
MSV3drs12243326
GWAS Ctlgrs12243326
GMAF0.1974
Max Magnitude0
? (C;C) (C;T) (T;T) 28


GWAS snp
PMID [PMID 20081857OA-icon.png]
Trait Two-hour glucose challenge
Title Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
Risk Allele C
P-val 1E-7
Odds Ratio 0.08 [0.06-0.10] mmol/L increase


[PMID 17934151] A variant of the transcription factor 7-like 2 (TCF7L2) gene and the risk of posttransplantation diabetes mellitus in renal allograft recipients.


[PMID 24157263] Polymorphisms of Transcription Factor-7-Like 2 (TCF7L2) gene in Tunisian women with polycystic ovaries syndrome (PCOS)


[PMID 23107111] Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects.


[PMID 23142382] Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Tunisian Arab subjects.


[PMID 32379818OA-icon.png] Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose.